Congenital Rubella is a clinically serious problem, which is due to maternal infection with Rubella virus during the first trimester of pregnancy. It may result in spontaneous abortion or in fetal infection leading to fetal birth defect.
The prevalence of Rubella antibodies and age of exposure to Rubella among premarital women's, the sera samples of 91 premarital women's were collected. All samples were screened for Rubella IgG antibodies using Enzyme linked immunosorbent assay. Off 91 sera, 77 were positive for Rubella IgG. All IgG negative sera were also IgM negative. These people are susceptible to reinfection of Rubella virus until they arte vaccinated .Thus; the individuals were advised to get immunized against Rubella virus.
Key words - Rubella, Young adults, Vaccination, Antibodies, ELIZA |